Osa Builder

OSA Builder provides total bone health in comprehensive, convenient and cost effective packets containing clinically-relevant quantities of microcrystalline hydroxyapatite concentrate (“MCHC”), cholecalciferol (D3) and choline-stabilized orthosilicic acid (“ch-OSA”). While the MCHC contributes to bone’s strength and stiffness; ch-OSA is vital for the synthesis of Type 1 collagen which determines bone’s flexibility and resistance to fracture. In addition, collagen provides “binding sites” for bone calcium.

All Center for Optimum Health Formulas Meet or Exceed cGMP quality Standards
Discussion
Calcium is vital to bone health and strength. However, calcium, as well as all bone minerals, must bind to core posts inside the bone. These flexible posts are made from collagen. With age-related loss of collagen, there become fewer and fewer of these bone-calcium binding sites, resulting in a reduction in bone mineral density. What’s more, the loss of bone collagen diminishes bone flexibility, resulting in a greater risk of fracture.
Collagen-Generating Complex
OSA BuilderTM contains patented, clinically-tested, choline-stabilized orthosilicic acid (ch-OSA). Ch-OSA links together single chains of amino acids to form collagen strands. The collagen strands create the core-post “binding sites” for calcium and other bone minerals. Oral supplementation of ch-OSA has been studied in chicks, rats, calves and humans.[1,2,3,4]
In a twelve-month, randomized, double-blind, placebo-controlled trial, (n=136 women; T score <1.5), a study group received 6 mg of ch-OSA along with 1000 mg calcium and 800 iu Vitamin D3, while another group received a placebo in addition to the same amounts of calcium and vitamin D3. Upon completion, the study group showed a 19% increase in serum procollagen type 1 N-terminal propeptide (PINP), the most sensitive bone formation marker, an overall positive trend for other bone formation markers (BAP, osteocalcin), and a 2.00% increase in BMD compared to the women taking only placebo, calcium and vitamin D3. Additionally, the ch-OSA group showed no adverse effects.[5]
An earlier study demonstrated that orthosilicic acid directly stimulates collagen type 1 synthesis in human osteoblast-like cells (bone-forming cells) and enhances osteoblastic differentiation.[6] Another OSA study demonstrated that the increase in collagen-responsible bone flexibility resulted in a greater resistance to physical stress.[7]
Mineral Complex
“Ossopan”, contains Center for Optimum Health’s micro-crystalline hydroxyapatite concentrate (MCHC), a premium, propri- etary, standardized extraction from New Zealand, the country that raises one of the world’s safest, most natural sources of bone. Ossopan provides a crystalline calcium and phosphorous matrix in the ideal physiological ratio of 2:1. Ossopan delivers bioactive growth factors and type I collagen, amino acids, glycosaminoglycans and a broad range of essential trace elements. During four decades of scientific research on Ossopan, numerous studies document the reversal of bone loss at therapeutic levels of supplementation.[8,9,10,11]
Vitamin D
Vitamin D in OSA Builder is provided as cholecalciferol, the form in which the vitamin is derived from cholesterol in the body and synthesized by sunlight on the skin. Vitamin D is needed to maintain normal blood levels of calcium and phosphate needed for normal bone metabolism. The active form of vitamin D regulates gene transcriptors that code for calcium-transporting and bone matrix proteins.
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Dosing
Consume content of packet once or twice a day as directed by your healthcare practitioner.
Supplement Facts
Serving Size: 1 Packet Servings Per Container: 60
(2) Ossopan 1100TM Capsules Amount %DV*
(1) ch-OSA® Capsule Amount %DV*
(1)
D3 Capsule Amount %DV*
Calcium (as MCHC†)    550 mg    56%
Vitamin D3 (Cholecalciferol)    2000 IU    500%
MCHC†    2200 mg
**
Silicon    3 mg (as Choline-Stabilized Orthosilicic Acid)
**
* Daily Value. ** Daily Value not established.
Other Ingredients for Ossopan 1100TM: HPMC (vegetable capsule) and magnesium stearate. Other Ingredients for ch-OSA®: Microcrystalline cellulose, HPMC (vegetable capsule), and purified water. Other Ingredients for D3: HPMC (vegetable capsule), microcrystalline cellulose, calcium carbonate, stearic acid, magnesium stearate and silica