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                    Oncomax ES, 60 Caps
  
    
                 
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							 * Whole number only
						             
             
          
           
		 
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       Discussion 
Sulforaphane, a naturally-occurring compound in broccoli that possesses 
antioxidant activity, was identified in 1992 by scientists at Johns 
Hopkins University School of Medicine. This isothiocyanate appeared to 
be responsible for the apparent correlation between diets rich in 
cruciferous vegetables and a lower incidence of cancer. Scien- tists 
subsequently determined that the compound present in the broccoli plant 
is the glucosinolate precursor of sulforaphane, known as “glucoraphanin”
 or “SGS.”[1] 
In 1997, this research group demonstrated that the SGS content of mature
 broccoli is highly variable and that SGS is present at much higher 
concentrations in broccoli seeds and three-day-old broccoli sprouts.[3] 
Specifically, the SGS content in 200 mg of broccoli seed extract or one 
ounce of broccoli sprouts is equivalent to the amount present in 20 oz. 
of market-stage broccoli.[2] Advanced, patented technology now enables 
Center for Optimum Health to include 100 mgs of SGS, the equivalent of 
approximately 3 3⁄4 pounds of broccoli, in a single capsule of OncoMax 
ESTM. 
Since 1992, SGS has been studied extensively at Johns Hopkins and other 
prestigious medical institutions around the globe, resulting in more 
than 400 published studies that support this natural phytochemical’s 
potential to achieve early protection against cell damage. 
What does SGS do? 
SGS is multidimensional, one of its primary actions being the activation
 of transcription factor, Nrf2, which induces increased production of 
phase 2 detoxifying enzymes and antioxidant enzymes. These enzymes 
generally last 72 hours or more, significantly longer than direct 
antioxidants such as vitamins C and E and beta carotene.[3-6] 
In addition, SGS supports cell cycle arrest and cell suicide in cells 
that have the potential to mutate.[3,7,8,9] It also provides support for
 the body’s protective response against harmful microbes[10,11] and its 
protective response against age-related CNS inflammation.[12] 
Additionally, SGS supports eye[13] and cardiovascular health 
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